CONTRAINDICATION: Do not use in people who will be allergic to nalmefene or any of the opposite components.

Morphine sulfate tablets might cause significant hypotension together with orthostatic hypotension and syncope in ambulatory sufferers. You can find amplified possibility in individuals whose capability to keep up hypertension has by now been compromised by a lessened blood quantity or concurrent administration of selected CNS depressant drugs (e.

Use the lowest helpful dosage with the shortest length of time consistent with specific affected individual cure goals [see Warnings and Safety measures (5)]. As the chance of overdose increases as opioid doses increase, reserve titration to greater doses of morphine sulfate tablets for individuals in whom decreased doses are insufficiently productive and in whom the predicted benefits of utilizing a higher dose opioid Obviously outweigh the considerable pitfalls.

Take into account prescribing naloxone, according to the affected individual's danger factors for overdose, like concomitant utilization of CNS depressants, a history of opioid use ailment, or prior opioid overdose. The existence of possibility factors for overdose shouldn't reduce the right management of soreness in almost any offered affected person.

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Morphine sulfate tablets may well impair the psychological or Actual physical qualities required to accomplish perhaps dangerous pursuits for instance driving a car or truck or working machinery.

CONTRAINDICATION: Do not use in clients who are allergic to nalmefene or any of one other ingredients.

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